EWALT 2023

Eastern and Western Association
of Liver Tumors (EWALT)

unimainz

Eastern and Western Association
of Liver Tumors (EWALT)

unimainz

The 25th Meeting of the Eastern and Western Association for Liver Tumors
EWALT 2023 | 8 – 10 November 2023 | Rheingoldhalle Mainz, Germany

Program

A THREE DAYS PROGRAM WITH WORLD LEADERS IN LIVER TUMOR MANAGEMENT

Wednesday, 08 November 2023

08:30 – 09:30

Registration & Welcome Coffee

09:30

Welcome
(H. Lang, Mainz)

09:35 – 10:00

Session 1 – Pathology of hepatobiliary malignancy 

  • Current advances in hepatopathology: Morphomolecular classification of liver tumors (B. Straub, Mainz)

10:00 – 11:25

Session 2 – what ´ s new in liver surgery

  • Liver volume modulation ( J.-N. Vauthey, Houston)
  • The concept of R1 vascular resection in surgery for HCC, ICC and CRLM (G. Torzilli, Milano)
  • The CUSA Clarity Soft Tissue Removal Study: Clinical Performance Investigation of the CUSA® Clarity Ultrasonic Surgical Aspirator System for Soft Tissue Removal during Liver Surgery (S. Gruttadauria, Palermo)
  • Impact of 3D visualization and planning in open and laparoscopic liver surgery (G. Stavrou, Saarbrücken)
  • Free paper: Intraoperative Ultrasound of the Liver: Immersive training in Reality (F. Huettl, Mainz)
  • Free video: Demonstration of Two-Surgeon Technique and Air Cholangiogram for Right Hepatectomy (D. W. Nelson, Houston)

11:30 – 12:40

Session 3 – multimodal therapies of HCC

  • Which systemic therapies for HCC are currently approved? (M. Reig, Barcelona)
  • Combined systemic / interventional approaches in the treatment of HCC (R. Klöckner, Lübeck)
  • Neoadjuvant/adjuvant treatment of HCC and liver resection / liver transplantation (P.R. Galle, Mainz)
  • Liver Resection after preoperative treatment of HCC (K. Hasegawa, Tokyo)
  • Free paper: Al derived body composition parameters as prognostic factors in patients with HCC undergoing TACE: Results from a multicenter study (L. Müller, Mainz)

12:40 – 14:00

Lunch break

13:15 – 14:00

Parallel Poster Sessions I 

14:00 – 15:05

Session 4 – minimally invasive surgery for HCC

  • Use of ICG in hepatobiliary surgery (G.L. Grazi, Firenze)
  • Technique of anatomic liver resection in the difficult segments (G. Honda, Tokyo)
  • Video: current approaches in laparoscopic and robotic liver resection (M. Schmelzle, Hannover)
  • Video: Laparoscopic anatomic resection of segment 5-8 with cranio caudal approach (F. Giuliante, Rome)
  • Free video: Anatomic Seg3-4a laparoscopic bisegmentectomy with left hepatic vein resection for hepatocellular carcinoma (A. Fontana, Torino)

15:05 – 15:25

Session 5 – Special lecture

  • Patterns of progression of HCC-implication for treatment? (M. Reig, Barcelona)

15:25 – 16:15

Session 6 – HCC and BCLC – current controversies

  • Resection in multifocal HCC: pro| con (Y. Kawaguchi, Tokyo | J. Ricke, Munich)
  • Resection in macrovascular invasion: pro | con (M. Donadon, Novara | A. Weinmann, Mainz)
  • Free paper: Preoperative prediction of posthepatectomy liver failure for hepatocellular carcinoma on CTscan by artificial intelligence and radiomics analyses (F. Milana, Mailand)

16:15 – 16:45

Coffee break

16:45 – 17:15

Session 7 – In memoriam C.E. Broelsch 

  • Life and work of Christoph E. Broelsch (H. Lang, Mainz)
  • Laudatio for LDLTx (D. Bröring / M. Malago, Riyadh)
  • International recognition of C.E. Broelsch (E. de Santibañes, Buenos Aires)

17:15 – 18:30

Session 8 – Transplant Oncology dedicated to C.E. Broelsch

  • Laparoscopic assisted LTx (S. Dokmak, Paris)
  • LTx for CRLM (U. Settmacher, Jena)
  • LTx for cholangiocarcinoma (S. Nadalin, Tübingen)
  • Liver transplantation for HCC (V. Mazzaferro, Milano)

18:30– 18:45

Welcome Adresses

18:45

Apéro 

Thursday, 09 November 2023

07:15 – 08:00: Prallel Sessions | Meet the expert session

  1. Molecular profiling, targeted therapy and immunotherapy–what do I need to know? (M. Möhler, Mainz |  Y. Kawaguchi, Tokyo)
  2. Role of tumor downstaging in transplantation of HCC (V. Mazzaferro, Milano |  J. Davide, Porto)
  3. Resection strategies in CRLM (G. Torzilli, Milano | F. Giuliante, Rome)
  4. Evolution of Robotic Liver Surgery (H. Tran Cao, Houston)
  5. Keys to safe hepatectomy (E. de Santibanes, Buenos Aires | A. Ferrero, Turino)

08:00 – 08:15

Coffee break

08:15 – 09:00

Sponsored Session 
SIRT in the treatment of liver tumors

09:05 – 09:45

Session 9 – Interventional treatment of liver tumors lecture

  • Stereotactic ablation as first line therapy of primary and secondary liver tumors? (R. Bale, Innsbruck)
  • Stereotactic Body Radiation Therapy  (H. Schmidberger, Mainz)
  • Liver-on-a-chip- A cancer mimicking model (Aistė Kielaitė-Gulla, Lithuania)

09:45 – 10:15

Coffee break

10:15 – 11:45

Session 10 – Treatment of iCCA

  • First-line therapies and molecular targeted therapy for iCCA (M. Möhler, Mainz)
  • Intra-arterial chemotherapy, pump therapy of unresectable iCCA (R. de Wilde, Amsterdam)
  • Liver resection for iCCA where is the limit? (J. Pratschke, Berlin)
  • Surgery for iCCA future perspectives (H. Tran Cao, Houston)
  • Minimally invasive approach to iCCA (A. Ruzzenente, Verona)

12:00 – 13:00

Industry Symposium
Past, Present  and future: HCC from different perspectives

12:00 – 14:15

Lunch break

13:30 – 14:15

Parallel Poster Sessions – Part 2

14:15 – 15:10

Session 11 – What´s new in resection of CRLM? 

  • The concept of parenchyma sparing resection (E. Dulundu, Istanbul)
  • Molecular profiling as a therapeutic stratifier in CRLM – ready for clinical use? (Y. Kawaguchi, Tokyo)
  • Liquid biopsy and ctDNA – where do we stand? (T.E. Newhook, Houston)
  • Free paper: TP53 Alteration and its Effect on Pathologic Response are Associated with Survival After Resection of Colorectal Liver Metastases (A. Haddad, Houston)

15:10 – 15:30

Session 12 – Special Lecture 

  • Cytoreductive surgery for CRLM –is it worthwhile? (R. Adam, Paris)

15:30 – 16:30

Session 13 – Free video session/Free paper session/My most difficult case

  • Case report: right hepatectomy without left portal vein (S.A. Lang, Essen)
  • Free video: Robot liver resection: reduced port approach and double bipolar clamp crushing method with video of anatomic segment 7 resection (Y. Sawa, Tokyo)
  • Free video: Laparoscopic hepatic resection with iatrogenic vascular injury (T. Castro, Vila Real)
  • Free video: Robotic mesohepatectomy for metastatic breast cancer of the liver (E. Birgin, Mannheim)
  • Case: Full robotic ALPPS in a 43y old female patient with liver adenomatosis (S. Katou, Münster)
  • Free video: Robotic major liver resections for HCC with vascular invasion (F. di Benedetto, Modena)

16:30 – 17:00

Coffee break

17:00 – 18:00

Session 14 – What´s new in CRLM? 

  • Minimally invasive resection of CRLM – Status quo (B. von Gohren Edwin, Oslo)
  • Video: Ante-Situm Resection for CRLM (E. de Santibañes, Buenos Aires)
  • Video: Laparoscopic tunnel operation for CRLM (A. Ferrero, Torino)
  • Free video: Laparoscopic anatomical small area hepatectomy, so called the cone units resection (Y. Kawamoto, Tokyo)
  • Free paper: Resection of major vessels in surgery for CRLM (J. Baumgart, Mainz)
  • Free paper: R1-vascular margin for liver colorectal cancer metastases: investigating the relationship between surgical margin, local risk of recurrence and OS (S. Famularo, Rom)

18:10 – 18:30

Session 15 – special lecture

  • Which innovation in liver surgery represented a progress? (J. Belghiti, Paris)

19:30

Congress evening
(tickets available and subject to charge)

Friday, 10 November 2023

07:15 – 8:00 PARALLEL SESSIONS | Meet the Expert session

  1. Laparoscopic Liver Surgery – Tips and tricks (G. Honda, Y. Kawaguchi | Tokyo)
  2. Vascular resection and reconstruction in liver surgery how I do it (S. Dokmak, Paris | T. Becker, Kiel)
  3. Tips and tricks in surgery of PHC (A. Guglielmi, Verona | H. Petrowsky, Zurich)
  4. When do I use molecular profiling and ctDNA in CRLM? (J.-N. Vauthey, Houston | T. Newhook, Houston)
  5. The role of Radioembolization as neodjuvant treatment for bridging/downstaging for liver surgery and transplantation (D. Balci, Istanbul | S. Nadalin, Tübingen)

08:00 – 08:15

Coffee break

08:15 – 08:35

Session 16 – Special lecture

  • Surgery for mesenchymal liver tumors (G.C. Sotiropoulos, Athens)

08:40 – 09:55

Session 17 – Perihilar cholangiocarcinoma I

  • Pathophysiology of the entero hepatic circuit and the role of biliary decompression (S. Olde-Damink, Maastricht)
  • Left sided versus right sided Resection for PHC (C.-W. D. Tzeng, Houston)
  • Is there a place for parenchyma sparing resections in PHC? (K.J. Oldhafer, Hamburg)
  • ALPPS for PHC (D. Balci, Istanbul)

10:00 – 10:30

Coffee break

10:30 – 11:30

Sponsored Session
XR support for personalized Liver surgery – The Future is now

11:30 – 12:00

Session 18 – Special lecture 

  • Ex vivo perfusion of liver and converting liver transplantation to elective surgery (P.A. Clavien, Zurich)

12:00 – 13:00

Lunch break

13:00 – 14:30

Session 19 – Perihilar cholangiocarcinoma II/ Masterclass Video

  • How to approach Klatskin Typ IV and contralateral vascular involvement (H. Lang, Mainz)
  • Minimal invasive approach to PHC (L. Aldrighetti, Milano)
  • Video: Left trisectionectomy for hilar cholangiocarcinoma (Y. Abe, Tokyo)
  • Video: Resection of PHC with vascular reconstruction (U. Neumann, Essen)
  • Video: H125678 B PV combined with REX shunt for locally advanced hilar cholangiocarcinoma (Y. Abe, Tokyo)
  • Video: Robotic resection of PHC (S. Fichtner Feigl, Freiburg)
  • Free paper: Portal and hepatic vein embolization in perihilar cholangiocarcinoma insights from the DRAGON and EuroLVD Registries (M. Dewulf, Maastricht)
  • Free paper: Three Dimensional Modelling Algorithm to Estimate the Longitudinal Tumor Extension and Margins of Surgery for Perihilar Cholangiocarcinoma (L. Alaimo, Verona)

14:30

Closing / Farewell

    Social Program

    Apéro

    On Wednesday, 8 November 2023 we invite all participants to the Apéro in the foyer/exhibition area starting at 19:00. Enjoy the evening with complimentary fingerfood and drinks.

    Social Dinner at Kurfürstliches Schloss Mainz

    On Thursday, 9 November 2023, 19:30, the Social Dinner will take place at
    Kurfürstl iches Schloss. Enjoy the congress evening in historic ambience.
    Address: Kurfürstliches Schloss | Peter-Altmeier-Allee 9 | 55116 Mainz
    The attendance at the social dinner is subject of charge. Please make sure to book your ticket in advance.

     

    Day Tickets will be available for purchase on-site.

    Accreditation

    Rhineland Palatinate Medical Association (Landesärztekammer Rheinland-Pfalz)

    The program of the 25th Meeting of the Eastern and Western Association for  Liver Tumors has been accredited with a total of 24 CME Points.

    European Accreditation Council for Continuing Medical Education (EACCME)

    The 25th Meeting of the Eastern and Western Association for Liver Tumors – EWALT 2023, Mainz, hybrid, Germany
    08/11/2023 – 10/11/2023, has been accredited by the European Accreditation Council for Continuing Medical Education
    (EACCME®) with 18.5 European CME credits (ECMEC®s).
    Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

    Ethical MedTech

    The 25th Meeting of the Eastern and Western Association for Liver Tumors in Mainz, Germany, has been rated compliant with the MedTech Europe Code of Ethical Business Practice.